| Name/Location | County | Open | Close | Comment |
| DALESIDE, Harrogate | N Yorkshire | 1987 | . | Name changed from Big End 1992. Also brews/brewed for Wolstenholme |
| DANELAW, Chellaston | Derbyshire | Unconfirmed | . | Source: Quaffale - Future Breweries. See also entry below
|
| DANELAW, Chellaston | Derbyshire | Unconfirmed | . | Follow progress on their website |
| Daniel Batham | . | . | . | See Batham |
| Daniel Thwaites | . | . | . | See Thwaites |
| Dark Horse | . | . | . | See Tilbury Ales |
| DARK STAR, Ansty, Haywards Heath | E Sussex | 1994 | . | Moved from The Evening Star PH Brighton 2001 |
| DARKTRIBE, Gunness, Scunthorpe | Lincolnshire | 1996 | . | Also brews for Duffield |
| DARLEY, Thorne | S Yorkshire | 1837 | 1986 | Acquired by Vaux 1978 |
| Darlings | . | . | . | See Longstone |
| Dartmough Inn | . | . | . | See Mc Bride's |
| DARWIN, Sunderland | Tyne & Wear | 1997 | . | Formerly Hodges. Acquired by Brewlab. Moved from Crook 2002. Plant ex Butterknowle. Also brews for High Force Hotel |
| Davenport Arms | . | . | . | See Worfield |
| DAVENPORTS, Birmingham | W Midlands | 1739 | 1989 | Acquired by Greenalls 1986 |
| Davis'es | . | . | . | See Grainstore |
| DEEPING, Market Deeping | Lincolnshire | 1996 | 1999 | . |
| DeEtchingham Arms | . | . | . | See Old Oak |
| Delph Brewery | . | . | . | See Batham |
| Delta Cloud Group | . | . | . | See Orchard Brewery Bar |
| DEMPSEYS, Dublin | Ireland | 1982 | 1986 | . |
| Dennis Brewery | . | . | . | See Simpkiss |
| DENT, Dent | Cumbria | 1990 | . | . |
| Derby Brewery | . | . | . | See Holt |
| DERBY BREWING, Derby | Derbyshire | 2004 | . | . |
| DERWENT, Consett | Co Durham | 1979 | 1981 | . |
| DERWENT, Silloth | Cumbria | 1997 | . | Moved from Cockermouth 1998 |
| DERWENT ROSE, Consett | Co Durham | 1997 | . | Located at The Grey Horse PH |
| Devanha Brewery | . | . | . | See Aberdeen Ales |
| Devenish, Redruth | . | . | . | See Redruth |
| DEVENISH, Weymouth | Dorset | 1742 | 1985 | Pubs sold to Boddingtons 1993. See also Redruth |
| DEVON ALES, Sauchie, Alloa, Clackmannonshire | Central | 1994 | . | Located at The Mansfield Arms PH |
| DIAMOND, Miles Platting | Gtr Manchester | Unconfirmed | . | Proposed brewery at The Ace of Diamonds PH. Source: Quaffale - Future Breweries |
| DILFORDS, Liverpool | Merseyside | 1985 | 1986 | . |
| DOCK, Southampton | Hampshire | 1981 | 1991 | Located at The Frog & Frigate PH. Owned by Ringwood |
| Dog & Parrot | . | . | . | See Newcastle Brewhouse |
| DOGHOUSE, Redruth | Cornwall | 2001 | . | . |
| DOLPHIN, Shrewsbury | Shropshire | 2000 | . | . |
| DONNINGTON, Stow-on-the-Wold | Gloucestershire | 1865 | . | IFBB Member |
| DONOGHUE, Grainthorpe, Louth | Lincolnshire | 2001 | 2004 | Moved from The Black Horse Inn, Grainthorpe 2002. Still brewing intermittently? |
| Dorothy Goodbody | . | . | . | See Wye Valley |
| DORSET, Weymouth | Dorset | 2004 | . | Formerly Quay. Located on the ex Groves/Devenish site |
| Dove Inn | . | . | . | See Wylye Valley |
| DOVE STREE INN, Ipswich | Suffolk | Unconfirmed | . | Source: Quaffale - Future Breweries
|
| Dovecote Brewery | . | . | . | See Nathan's Fine Ales |
| DOW BRIDGE, Catthorpe, Lutterworth | Leicestershire | 2002 | . | . |
| DOWN ROYAL, Lisburn | N I | 1982 | 1988 | Aka Foyle? |
| DOWNHAM, Downham Market | Norfolk | 1982 | 1985 | Located at The Castle Hotel |
| DOWNTON, Downton | Wiltshire | 2003 | . | . |
| DRAGON ALES, ? | South Wales? | Unconfirmed | . | Source: Quaffale - Future Breweries
|
| Dressers Arms | . | . | . | See Old Wheelton |
| DRIFTWOOD, Trevaunance Cove, St Agnes | Cornwall | 2000 | . | Plant ex Horsebridge. Located opposite The Driftwood Spars Inn |
| DRUMMONDS, Sheffield | S Yorkshire | 1999 | 2000 | Plant ex Flannerys |
| Drunken Duck | . | . | . | See Barngates |
| DRYBOROUGH, Edinburgh | Lothian | 1750 | 1987 | Bought by Allied Lyons (Tetleys) from Watney 1987 |
| DUBLIN, Smithfield, Dublin | Ireland | 1996 | . | Keg/bottled only? |
| Dudgeon & Co | . | . | . | See Belhaven |
| DUFFIELD, Harmston | Lincolnshire | 1996 | 2001 | Originally located at The Thorold Arms PH. Merged with DarkTribe |
| DUKE OF NORFOLK, Notting Hill | London W11 | 1990 | 1993 | Plant ex Jolly Fenman. Located at The Duke of Norfolk PH (Clifton Inns/Watneys) |
| Duke of York | . | . | . | See Goose & Firkin |
| DUNKERY ALES, Exford | Somerset | Unconfirmed | . | Source: Quaffale - Future Breweries
|
| DUNN & PATTERSON, Bristol | Gloucestershire | 1984 | 1985 | . |
| DUNN PLOWMAN, Kington | Herefordshire | 1998 | . | Former Solstice site. Plant ex S P Sporting Ales |
| DUNN PLOWMAN, Leominster | Herefordshire | 1992 | 1994 | Located at The Black Horse PH. See also Marches |
| DUNN PLOWMAN, Lingen | Herefordshire | 1987 | 1988 | Located at The Old Royal George PH |
| Dunnings Mill | . | . | . | See Grinstede |
| DURHAM, Bowburn | Co Durham | 1994 | . | . |
| DUTTONS, Blackburn | Lancashire | 1799 | 1978 | Acquired by Whitbread 1964 |
| DWAN'S, Thurles, Co Tipperary, Munster | Ireland | 1999 | . | Beers served under gas pressure |
| DYFFRYN CLWYD, Denbigh | N E Wales | 1993 | 1998 | Aka Bragdy Dyffryn Clwyd. Brands sold to Flannerys |