| Name/Location | County | Open | Close | Comment |
| Eagle Brewery | . | . | . | See Wells |
| EARL SOHAM, Earl Soham | Suffolk | 1984 | . | Plant ex Brightlingsea. Moved from The Victoria PH 2002 |
| EASINGWOLD, Easingwold | N Yorkshire | 1996 | 2000 | Located at The Station Hotel |
| EAST GRINSTEAD, East Grinstead | W Sussex | 1985 | 1985 | Grinstede Brewery at The Dunnings Mill PH. Also brewed 80-82 |
| EAST WEST ALES, ? | ? | No brewery | . | Beer wholesaler. 'House' beers from Brewery on Sea & Cotleigh |
| EASTWOOD & SANDERS, Elland | W Yorkshire | 2002 | . | Merged Barge & Barrel and West Yorkshire breweries |
| EASTWOOD'S, Longwood | W Yorkshire | 1996 | 1997 | Also brewed 1993-4. See also Barge & Barrel |
| ECCLESHALL, Eccleshall | Staffordshire | 1994 | . | Slaters Brewery. Located at The George Hotel |
| EDALE, Edale, Hope Valley | Derbyshire | 2003 | . | Also owns the Crown Brewery, Sheffield & the Wellington brands |
| Edgcote | . | . | . | See Warden |
| Edmundbyers | . | . | . | See Old Barn |
| EGLESBRECH, Falkirk | Central | 2000 | . | Located (upstairs) at The 'Behind the Wall' leisure complex |
| EGYPTIAN SAND & GRAVEL, Dewsbury | W Yorkshire | 1999 | . | Plant ex Blackmoor. Located at The Leggers Inn. Name changed from Sunset 2002 |
| ELDRIDGE POPE, Dorchester | Dorset | 1837 | 1997 | Aka Thomas Hardy. See also Hardy Burtonwood |
| ELGOOD, Wisbech | Cambridgeshire | 1786 | . | North Brink Brewery. IFBB Member |
| Elsecar | . | . | . | See Barnsley |
| ELVEDON ALES, Elvedon | Suffolk | 2004 | . | . |
| ELY, Cardiff | Glamorgan | 1855 | 1978 | Acquired by Rhymney Breweries 1959 & by Whitbread 1966 |
| EMERALD, Roscommon | Ireland | 1999 | . | . |
| EMPIRE, Huddersfield | W Yorkshire | 2004 | . | . |
| ENFIELD, Enfield | London N? | Unconfirmed | . | Source: Quaffale - Future Breweries |
| ENGINEERS ARMS, Henlow | Bedfordshire | Unconfirmed | . | Source: Quaffale - Future Breweries & New Imbiber No.4
|
| ENVILLE, Cox Green, Enville, Stourbridge | Staffordshire | 1993 | . | Also brews/brewed for Gornal |
| Eric's | . | . | . | See Reckless |
| Eshaldwell Brewery | . | . | . | See Bentleys |
| EVAN EVANS, Llandeilo, Carmarthanshire | W Wales | 2004 | . | Headed by Simon Buckley |
| EVAN, EVANS BEVAN, Neath | Glamorgan | 1846 | 1972 | Acquired by Whitbread 1967 |
| Evening Star | . | . | . | See Dark Star |
| EVERARDS, Burton-upon-Trent | Staffordshire | 1898 | 1983 | Trent Brewery (renamed Tiger c1970). See also Heritage, Bevvied Bull & Old Cottage |
| EVERARDS, Narborough, Leicester | Leicestershire | 1849 | . | Brewery rebuilt 1985. Also brews for Scottich Courage. IFBB Member |
| EVESHAM, Evesham | Worcestershire | 1992 | . | Located at The Green Dragon PH. Aka Murphy |
| Exchange Brewery | . | . | . | See Tennants |
| EXE VALLEY, Silverton, Exeter | Devon | 1984 | . | Name changed from Barron 1991 |
| Exeter Arms | . | . | . | See Blencowe |
| EXMOOR, Wiveliscombe | Somerset | 1980 | . | Site ex Hancocks (closed 1959). Name changed from Golden Hill 1988 |