| Name/Location | County | Open | Close | Comment |
| Saddle Inn | . | . | . | See Featherstone |
| SADDLEWORTH, Uppermill, Oldham | Gtr Manchester | 1997 | . | Located at The Church Inn PH |
| St AUSTELL, St Austell | Cornwall | 1851 | . | Also brews for ex-Ferguson. IFBB Member |
| St Clements | . | . | . | See First in Last Out |
| St Edmunds Head | . | . | . | See Old Cannon |
| St GEORGE'S, Callow End, Malvern | Worcestershire | 1998 | . | . |
| St GILES IN THE WOOD, Great Torrington | Devon | 1998 | 1999 | Plant ex Sutton. See also Clearwater |
| St Helens College | . | . | . | See Beecham's |
| St PETER'S, South Elmham, Bungay | Suffolk | 1996 | . | . |
| Sair Inn | . | . | . | See Linfit |
| SALAMANDER, Bradford | W Yorkshire | 2000 | . | . |
| Sallies | . | . | . | See Britannia |
| SALOPIAN, Shrewsbury | Shropshire | 1995 | . | Ceased part 1997 |
| SAM POWELL, Newtown, Powys | Mid Wales | 1983 | 1991 | Plant & Brands ex Powys. See also Wood |
| SAM TRUEMAN, Medmenham | Buckinghamshire | 1995 | 2002 | Formerly Little. Business Training Centre brewery! |
| Samuel Allsopp | . | . | . | See Allsopps |
| SAMUEL SMITH, Tadcaster | W Yorkshire | 1758 | . | See also Melbourn Brothers |
| Samuel Webster | . | . | . | See Websters |
| SANDOWN, Sandown | I O W | 1996 | 1998 | Located at The Old Comical PH (ex Cask & Codpiece). Aka Burts/Hartridges. See also Ushers |
| SARAH HUGHES, Sedgley, Dudley | W Midlands | 1987 | . | Located at The Beacon Hotel. Also brewed c1860-c1957 |
| SARAH'S HOPHOUSE, Golborne, Warrington | Gtr Manchester | 1999 | 2003 | Located at The Railway Inn |
| SARK, Sark | C I | 1983 | 1983 | . |
| SAWBRIDGEWORTH, Sawbridgeworth | Hertfordshire | 2000 | . | Located at The Gate Inn |
| SAXON CROSS, Buxton | Derbyshire | 1979 | 1987 | Aka Winkles |
| SCANLON'S, Yiewsley | Middlesex | 1996 | 1997 | See also Scanlon's Fine Ales |
| SCANLON'S FINE ALES, Uxbridge | Middlesex | No brewery | . | Formerly Scanlons. Contract brewed by O'Hanlon's & Vale |
| SCARECROW, Arreton | I O W | 2002 | . | . |
| SCATTOR ROCK, Christow, Exeter | Devon | 1998 | . | . |
| Scotland's Craft Brewers Co-operative | No brewery | . | . | See Bridge of Allan, Lugton & Sulwath |
| Scottish & Newcastle | . | . | . | See Scottish Courage, Home, Websters & Yorkshire Grey |
| Scottish Brewers | . | . | . | Merger of Wm McEwan & Wm Younger 1931. Merged with Newcastle Breweries 1960 to become Scottish & Newcastle |
| Scottish Courage | . | . | . | Formed by acquisition of Courage by S&N 1995 |
| SCOTTISH COURAGE, Bristol | Gloucestershire | 1730? | 2000 | Georges Brewery. Acquired by Courage 1961 & by Scottish & Newcastle 1995 |
| SCOTTISH COURAGE, Edinburgh | Lothian | 1856 | . | Wm McEwan's Fountain Brewery (rebuilt 1974). Merged with Wm Younger 1931 & with Newcastle breweries 1960 |
| SCOTTISH COURAGE, Manchester | Gtr Manchester | ? | . | Royal brewery. Keg only (Harp Lager) |
| SCOTTISH COURAGE, Masham | N Yorkshire | 1827 | . | Theakston, aka T & R Theakston. Acquired by Matthew Brown 1984 & by S&N 1987 |
| SCOTTISH COURAGE, Newcastle-upon-Tyne | Tyne & Wear | Reg 1890 | . | Tyne Brewery |
| SCOTTISH COURAGE, Reading | Berkshire | ? | . | Aka Worton Grange. Acquired from Courage by Scottish & Newcastle 1995. Keg only |
| SCOTTISH COURAGE, Tadcaster | W Yorkshire | 1757 | . | John Smith's brewery. Acquired by Courage 1970 & by Scottish & Newcastle 1995 |
| SCOTT'S, Lowestoft | Suffolk | 1988 | 1999 | Plant ex Sevenoaks. Name changed from Scotties 1992/3 |
| Sea Lion | . | . | . | See Olde Bull & Bush |
| SELBY, Selby | N Yorkshire | 1972 | . | Also brewed 1894-1954 |
| SEVENOAKS, Seal Chart | Kent | 1981 | 1986 | Located at The Crown Point Inn |
| SHACKLEFORD, Shackleford | Surrey | 1992 | 1994 | Located at The Cyder House PH. See also Baynards |
| SHAKESPEARE'S, Stratford-upon-Avon | Warwickshire | Unconfirmed | . | Source: Quaffale - Future Breweries |
| SHARDLOW, Cavendish Bridge | Leicestershire | 1993 | . | . |
| SHARP'S, Wadebridge | Cornwall | 1994 | . | . |
| SHAWS, Dukinfield | Gtr Manchester | 2002 | . | . |
| Sheaf of Arrows | . | . | . | See Cranborne |
| SHEPHERD & Co, Bitteswell | Leicestershire | 1998 | . | Ex Man in the Moon. No Real ale |
| SHEPHERD NEAME, Faversham | Kent | 1698 | . | IFBB Member |
| Sherwood Forest | . | . | . | See Bateman |
| Ship | . | . | . | See Solva |
| SHIP & MITRE, Liverpool | Merseyside | Unconfirmed | . | Source: Quaffale - Future Breweries |
| Ship & Plough | . | . | . | See Blewitt's |
| SHIPSTONE, Basford, Nottingham | Nottinghamshire | 1852 | 1991 | Star Brewery. Aka James Shipstone. Acquired by Greenalls 1978 |
| SHIRES, Shefford | Bedfordshire | 1995 | 1996 | Plant ex Judges |
| SHOES, Norton Canon | Herefordshire | 1994 | . | Located at The Three Horseshoes PH |
| Shore Hotel | . | . | . | See Old Laxey |
| SHRALEY BROOK, Shraley Brook | Staffordshire | 1998 | 2001 | Site & plant leased from Rising Sun |
| Shrewsbury & Wem | . | . | . | See Wem |
| SHUGBOROUGH, Milford | Staffordshire | 1996 | . | Staffordshire County Museum. Occasional brews by Titanic. Also brewed 1990 |
| SILVER STREAM, Horsham | W Sussex | 2001 | . | Occasional brews using Hepworth plant |
| SILVERTHORNE GWENT ALES, Pontnewdd | Gwent | 1984 | 1985 | Ex Gwent Ales. Moved to Lamb Inn (Pontynewdd?) |
| SIMMONDS,
Reading | Berkshire | 1768 | 1979 | Acquired by Courage 1960 |
| SIMON'S TOWER BRIDGE, Southwark | London SE1 | 1980 | 1981 | See also Bridge House |
| SIMPKISS, Brierley Hill | W Midlands | 1919 | 1985 | Dennis Brewery. Aka JPS. Acquired by Greenalls 1985. See also Enville. |
| Simpson & Simpson | . | . | . | See Brown Cow |
| Sir William Peel | . | . | . | See Old Stables |
| SIX BELLS, Bishops Castle | Shropshire | 1997 | . | Located at The Six Bells PH. Also brews for Ystwyth Ales |
| SKINNER'S, Truro | Cornwall | 1997 | . | Plant ex Aberdeenshire |
| Skinners, Brighton | . | . | . | See Dark Star |
| Slaters Brewery | . | . | . | See Eccleshall |
| SLAUGHTERHOUSE, Warwick | Warwickshire | 2003 | . | Plant ex Church End |
| SLIGACHAN, Isle of Skye | Highlands | Unconfirmed | . | Source: New Imbiber No.4 |
| SMILES, Bristol | Gloucestershire | 1977 | . | Moved from Bells Diner 1978 & name changed from Paynes |
| Smith (John) | . | . | . | See Scottish Courage, Tadcaster |
| Smith (Samuel) | . | . | . | See Samuel Smith |
| SNOWDONIA, Gellilydan, Blaenau Festiniog, Gwynedd | N W Wales | 1992 | 1995 | Aka Barrys/Bryn Arms |
| SNOWDONIA, Waunfawr, Caernarfon, Gwynedd | N W Wales | 1998 | . | Located at The Snowdonia Park Hotel |
| Soho Brewing Co | . | . | . | See Freedom |
| Sole Bay Brewery | . | . | . | See Adnams |
| SOLSTICE, Kington | Herefordshire | 1993 | 1995 | Former Dunn Plowman plant. Located at The Queens Head PH. Plant sold to Marches |
| SOLVA, Haverfordwest, Pembroke | W Wales | 1993 | 1996 | Located at The Ship PH |
| SOMERSET (ELECTRIC), Halse, Taunton | Somerset | 2004 | . | Located at The New Inn |
| South Eastern | . | . | . | See Hilton |
| SOUTH HAMS, Stokenham, Kingsbridge | Devon | 2004 | . | Formerly Sutton then Stokeley |
| South Yorkshire | . | . | . | See Barnsley |
| Southern Brewers | . | . | . | See Pig & Whistle |
| SOUTHPORT, Blowick, Southport | Merseyside | 2004 | . | Plant ex Banfield/Buntingford/3 Rivers |
| SOUTHSEA, Portsmouth | Hampshire | 1982 | 1985 | Aka Old Lion |
| Southwick Brewhouse | . | . | . | See Golden Lion |
| SP SPORTING ALES, Stoke Prior, Leominster | Herefordshire | 1996 | 2001? | Plant sold to Dunn Plowman, Kington |
| SPECTRUM, Bradenham, Thetford | Norfolk | 2002 | . | Organic beers. Shares site with Blue Moon |
| Speedwell Inn | . | . | . | See Townes |
| SPIKES, Southsea | Hampshire | 1994 | 2000? | Located at The Wine Vaults PH |
| SPINNAKER, Lancing | W Sussex | 1993 | 2001? | Plant ex Dickens. Formerly Brewery on Sea. Also brews for East West Ales |
| SPINNING DOG, Hereford | Herefordshire | 2000 | . | Located at The Victory PH (ex Jolly Roger site). Brewing ex Flannery's brands? |
| Springfield Brewery | . | . | . | See Bass, Wolverhampton |
| SPRINGHEAD, Sutton-on-Trent, Newark | Nottinghamshire | 1990 | . | Moved 1994. Ceased part 1997/8 |
| Stable Brewery | . | . | . | See Maldon Brewing |
| Stables Brewery | . | . | . | See Humpty Dumpty |
| Stag Tavern, Stotford | . | . | . | See Abel Brown's |
| Stag Tavern, Stowmarket | . | . | . | See Bury Street |
| STAG & GRIFFIN, Tatling End, Gerrards Cross | Buckinghamshire | 1996 | 1997 | Moved to Viking, Broadstairs |
| Stag & Hounds | . | . | . | See Parish & John o'Gaunt |
| Stag Brewery | . | . | . | See Watneys, Mortlake |
| STALLION ALES, Helland, Bodmin | Cornwall | 1983 | 1987 | Moved from Long Barn, Cippenham 1985 |
| STANWAY, Cheltenham | Gloucestershire | 1993 | . | . |
| STAR, Cambridge | Cambridgeshire | 1822 | 1972 | Acquired by Tolly Cobbold 1934 |
| STAR INN, Crowlas | Cornwall | Unconfirmed | . | Source: Quaffale - Future Breweries & New Imbiber No.4 |
| STAR, Norwich | Norfolk | 1981 | 1982 | Located at The Golden Star PH. Aka Turners Star. Plant sold to Fox & Hounds, Barley |
| Star Brewery | . | . | . | See Ind Coope, Romford |
| Star Brewery | . | . | . | See Shipstone |
| Star, St Peter Port | . | . | . | See Tipsy Toad |
| STARKEY, KNIGHT & FORD, Tiverton | Devon | 1852 | 1982 | Acquired by Whitbread 1962 |
| Station Hotel | . | . | . | See Easingwold |
| STATION HOUSE, Ellesmere Port | Merseyside | Unconfirmed | . | Source: Quaffale - Future Breweries |
| STATION INN, Guiseley | W Yorkshire | 1982 | 1987 | Allied (Tetley) pub brewery |
| STEAM PACKET, Knottingley | W Yorkshire | 1990 | 1998 | Plant moved to Kent Garden |
| STEAMBOAT, Sawley | Nottinghamshire | 1987 | 1989 | Closed 1991? |
| STEAMIN' BILLY, Oadby | Leicestershire | No brewery | . | Beers brewed by Grainstore |
| STEWART, Edinburgh | Lothian | 2004 | . | . |
| STOCKS, Doncaster | S Yorkshire | 1981 | 1996 | Located at The Hallcross PH. Closed by Century Inns. See also Hull |
| Stokeley | . | . | . | See South Hams |
| STONEHENGE, Netheravon, Salisbury | Wiltshire | 1984 | . | Plant ex Swimbidge. Ownership & name changed from Bunces 1993 |
| STONES, Sheffield | S Yorkshire | 1898 | 1999 | Aka William Stones. Acquired by Bass 1968 |
| STONY ROCK, Waterhouses, Stoke on Trent | Staffordshire | 1997 | 2000 | . |
| STORM BREWING, Macclesfield | Cheshire | 1998 | . | Originally named Bollin? |
| Strangeways Brewery | . | . | . | See Interbrew Manchester |
| STRANGFORD LOUGH, Killyleagh, County Down | Ireland | Unconfirmed | . | Source: Quaffale - Future Breweries |
| STRATHALBYN, Dalmuir | Strathclyde | 1982 | 1987 | . |
| STRATORE, Thornton, Kirkaldy | Fife | 1996 | 2000 | Formerly Backdykes. Also brewed Malcolm Ales |
| STRAWBERRY BANK, Strawberry Bank | Cumbria | 1997 | 2000? | Masons Arms pub brewery. Former home of Lakeland Brewing Co. |
| STREETS OF LONDON, East Molesey | Surrey | 1982 | 1984 | Whitbread pub brewery |
| STRONG, Romsey | Hampshire | 1858 | 1981 | Horsefair Brewery. Acquired by Whitbread 1969 |
| STUDLEY, Studley | Warwickshire | 1978 | 1982 | Part of Seven Wonders Inns |
| STUMPY'S, Swanmore | Hampshire | 2004 | . | . |
| STYLE & WINCH, Maidstone | Kent | 1806 | 1971 | Acquired by Barclay Perkins (Courage) 1929 |
| Suddaby's Crown Hotel | . | . | . | See Malton |
| SULWATH, Castle Douglas | Dumfries & Galloway | 1997 | . | Moved from Southerness 2000 |
| SUMMERSKILLS, Billacombe, Plymouth | Devon | 1983 | . | Plant ex Penrhos. Moved from Bigbury on Sea 1985. Ceased 1986-90 |
| Sun Inn | . | . | . | See Corvedale |
| Sunset Cider & Wine Ltd | . | . | . | See Egyptian Sand & Gravel |
| SURREY HILLS, Shere | Surrey | Unconfirmed | . | Source: Quaffale - Future Breweries & New Imbiber No.4. See also entry below |
| SURREY HILLS, Shere | Surrey | Unconfirmed | . | Follow progress on their website |
SUSSEX, Pett | E Sussex | 1998 | 2004 | Site & plant ex Pett. Formerly Old Forge then Forge. Located opposite The Two Sawyers PH |
| Sussex Brewery P H | . | . | . | See Hermitage |
| SUSSEX, Pulborough | W Sussex | 1980 | 1983 | Ownership change/moved from Edburton, Nr Poynings 1982 |
| SUTHERLAND, Edinburgh | Lothian | 1996 | 1997 | . |
| SUTHWYK ALES, Suthwick, Fareham | Hampshire | No brewery | . | Brewed by Hop Back using barley from South Hams |
| SUTTON, Plymouth | Devon | 1994 | 2004 | See also South Hams |
| SWALE, Grafty Green | Kent | 1995 | 2003 | Moved several times & became Tun, Vine & Press 2000-01. Plant sold to Whitstable |
| SWALED ALE, Gunnerside, Richmond | N Yorkshire | 1995 | 2001? | . |
| Swan PH | . | . | . | See John Joules & Son |
| SWAN ON THE GREEN, West Peckham, Maidstone | Kent | 2000 | . | . |
| SWANNELLS, Kings Langley | Hertfordshire | 1982 | 1983 | . |
| SWANNELLS, Kings Langley | Hertfordshire | 1982 | 1983 | . |
| SWANSEA, Bishopston, Swansea | Glamorgan | 1996 | . | Located at The Joiners Arms PH |
| SWEET WILLIAM, Leyton | London E10 | 2000 | . | Located at The William IV PH |
| SWIMBRIDGE, Barnstable | Devon | 1981 | 1983 | . |