| Name/Location | County | Open | Close | Comment |
| UFFORD, Ufford | Cambridgeshire | Unconfirmed | . | Proposed brewery at The White Hart PH. Source: Quaffale - Future Breweries & New Imbiber No.4 |
| ULEY, Dursley | Gloucestershire | 1985 | . | . |
| UNCLE STUART'S, Norwich | Norfolk | 2003 | . | . |
| Unicorn Brewery | . | . | . | See Robinsons |
| UNICORN, Ketley | Shropshire | 1986 | 1988 | . |
| UNION, Hayes | Middlesex | 1982 | 1983 | Aka B & W Beer Co |
| Upper Agbrigg | . | . | . | See Holme Valley |
| USHERS, Edinburgh | Lothian | 1817 | 1981 | Acquired by Allied (Tetleys) 1980 |
| USHERS, Trowbridge | Wiltshire | 1824 | 2000 | Management buyout 1991 ex Courage. Also owned Burts brands. & brewed for Gibbs Mew. Closed by InnSpired. |